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Antioxidants prevent inflammation and preserve the optic projection and visual function in experimental neurotrauma

We investigated the role of oxidative stress and the inflammasome in trauma-induced axon degeneration and vision loss using a mouse model. The left eyes of male mice were exposed to over-pressure air waves. Wild-type C57Bl/6 mice were fed normal, high-vitamin-E (VitE), ketogenic or ketogenic-control...

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Detalles Bibliográficos
Autores principales: Bernardo-Colón, Alexandra, Vest, Victoria, Clark, Adrienne, Cooper, Melissa L., Calkins, David J., Harrison, Fiona E., Rex, Tonia S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203845/
https://www.ncbi.nlm.nih.gov/pubmed/30367086
http://dx.doi.org/10.1038/s41419-018-1061-4