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Uric acid enhances alteplase-mediated thrombolysis as an antioxidant

Uric acid (UA) therapy may prevent early ischemic worsening after acute stroke in thrombolysis patients. The aim of this study was to examine the influence of UA on the thrombolytic efficacy of alteplase in human blood samples by measuring thrombolysis under flow conditions using a newly developed m...

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Detalles Bibliográficos
Autores principales: Kikuchi, Kiyoshi, Setoyama, Kentaro, Tanaka, Eiichiro, Otsuka, Shotaro, Terashi, Takuto, Nakanishi, Kazuki, Takada, Seiya, Sakakima, Harutoshi, Ampawong, Sumate, Kawahara, Ko-ichi, Nagasato, Tomoka, Hosokawa, Kazuya, Harada, Yoichiro, Yamamoto, Mika, Kamikokuryo, Chinatsu, Kiyama, Ryoji, Morioka, Motohiro, Ito, Takashi, Maruyama, Ikuro, Tancharoen, Salunya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203847/
https://www.ncbi.nlm.nih.gov/pubmed/30367108
http://dx.doi.org/10.1038/s41598-018-34220-1