Cargando…

Uric acid enhances alteplase-mediated thrombolysis as an antioxidant

Uric acid (UA) therapy may prevent early ischemic worsening after acute stroke in thrombolysis patients. The aim of this study was to examine the influence of UA on the thrombolytic efficacy of alteplase in human blood samples by measuring thrombolysis under flow conditions using a newly developed m...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kikuchi, Kiyoshi, Setoyama, Kentaro, Tanaka, Eiichiro, Otsuka, Shotaro, Terashi, Takuto, Nakanishi, Kazuki, Takada, Seiya, Sakakima, Harutoshi, Ampawong, Sumate, Kawahara, Ko-ichi, Nagasato, Tomoka, Hosokawa, Kazuya, Harada, Yoichiro, Yamamoto, Mika, Kamikokuryo, Chinatsu, Kiyama, Ryoji, Morioka, Motohiro, Ito, Takashi, Maruyama, Ikuro, Tancharoen, Salunya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203847/ https://www.ncbi.nlm.nih.gov/pubmed/30367108 http://dx.doi.org/10.1038/s41598-018-34220-1

Ejemplares similares

Edaravone, a Synthetic Free Radical Scavenger, Enhances Alteplase-Mediated Thrombolysis
por: Kikuchi, Kiyoshi, et al.
Publicado: (2017)

E8002 Inhibits Peripheral Nerve Adhesion by Enhancing Fibrinolysis of l-Ascorbic Acid in a Rat Sciatic Nerve Model
por: Kikuchi, Kiyoshi, et al.
Publicado: (2020)

Application of a Novel Anti-Adhesive Membrane, E8002, in a Rat Laminectomy Model
por: Kikuchi, Kiyoshi, et al.
Publicado: (2018)

E8002 Reduces Adhesion Formation and Improves Joint Mobility in a Rat Model of Knee Arthrofibrosis
por: Takada, Seiya, et al.
Publicado: (2022)

1,5-anhydro-D-fructose induces anti-aging effects on aging-associated brain diseases by increasing 5’-adenosine monophosphate-activated protein kinase activity via the peroxisome proliferator-activated receptor-γ co-activator-1α/brain-derived neurotrophic factor pathway
por: Kikuchi, Kiyoshi, et al.
Publicado: (2023)

HMGB1 Promotes Intraoral Palatal Wound Healing through RAGE-Dependent Mechanisms
por: Tancharoen, Salunya, et al.
Publicado: (2016)

The Efficacy of Edaravone (Radicut), a Free Radical Scavenger, for Cardiovascular Disease
por: Kikuchi, Kiyoshi, et al.
Publicado: (2013)

The effect of exercise frequency on neuropathic pain and pain-related cellular reactions in the spinal cord and midbrain in a rat sciatic nerve injury model
por: Sumizono, Megumi, et al.
Publicado: (2018)

Diurnal Profiles of Locomotive and Household Activities Using an Accelerometer in Community-Dwelling Older Adults with Musculoskeletal Disorders: A Cross-Sectional Survey
por: Sakakima, Harutoshi, et al.
Publicado: (2020)

Potential of the Angiotensin Receptor Blockers (ARBs) Telmisartan, Irbesartan, and Candesartan for Inhibiting the HMGB1/RAGE Axis in Prevention and Acute Treatment of Stroke
por: Kikuchi, Kiyoshi, et al.
Publicado: (2013)

Correction: Kikuchi, K., et al., Potential of the Angiotensin Receptor Blockers (ARBs) Telmisartan, Irbesartan, and Candesartan for Inhibiting the HMGB1/RAGE Axis in Prevention and Acute Treatment of Stroke. Int. J. Mol. Sci. 2013, 14, 18899–18924.
por: Kikuchi, Kiyoshi, et al.
Publicado: (2014)

Overexpression of Receptor for Advanced Glycation End Products and High-Mobility Group Box 1 in Human Dental Pulp Inflammation
por: Tancharoen, Salunya, et al.
Publicado: (2014)

Cardiovascular risk factors are associated with augmented thrombogenicity in healthy individuals: analysis using the Total Thrombus-formation Analysis System
por: Oda, Yuu, et al.
Publicado: (2021)

Analysis of the Effects of Ninjin’yoeito on Physical Frailty in Mice
por: Otsuka, Shotaro, et al.
Publicado: (2022)

A modified microchip-based flow chamber system for evaluating thrombogenicity in patients with thrombocytopenia
por: Atari, Bengo, et al.
Publicado: (2020)

Disruption of Midkine gene reduces traumatic brain injury through the modulation of neuroinflammation
por: Takada, Seiya, et al.
Publicado: (2020)

Effects of low-intensity exercise on spontaneously developed knee osteoarthritis in male senescence-accelerated mouse prone 8
por: Norimatsu, Kosuke, et al.
Publicado: (2023)

Preventive effects of Morus alba L. anthocyanins on diabetes in Zucker diabetic fatty rats
por: SARIKAPHUTI, ARIYA, et al.
Publicado: (2013)

Effects of different remote ischemia perconditioning methods on cerebral infarct volume and neurological impairment in rats
por: Otsuka, Shotaro, et al.
Publicado: (2023)

Circulating histone H3 levels in septic patients are associated with coagulopathy, multiple organ failure, and death: a single-center observational study
por: Yokoyama, Yayoi, et al.
Publicado: (2019)

Circulating Syndecan-1 as a Predictor of Persistent Thrombocytopenia and Lethal Outcome: A Population Study of Patients With Suspected Sepsis Requiring Intensive Care
por: Hatanaka, Kosaku, et al.
Publicado: (2021)

Differential Regulation of Damage-Associated Molecular Pattern Release in a Mouse Model of Skeletal Muscle Ischemia/Reperfusion Injury
por: Furubeppu, Hiroaki, et al.
Publicado: (2021)

Chronic Ingestion of High Dosed Phikud Navakot Extraction Induces Mesangiolysis in Rats with Alteration of AQP1 and Hsp60 Expressions
por: Kengkoom, Kanchana, et al.
Publicado: (2015)

In Vitro Protective Effect of Phikud Navakot Extraction on Erythrocyte
por: Kengkoom, Kanchana, et al.
Publicado: (2016)

Experimental Scedosporiosis Induces Cerebral Oedema Associated with Abscess regarding Aquaporin-4 and Nrf-2 Depletions
por: Ampawong, Sumate, et al.
Publicado: (2019)

Intravenous thrombolysis with alteplase in the treatment of acute cerebral infarction
por: Gao, Lilin, et al.
Publicado: (2022)

Stability of alteplase for ultrasound-facilitated catheter-directed thrombolysis
por: Fanikos, John, et al.
Publicado: (2021)

Alteplase or tenecteplase for thrombolysis in ischemic stroke: An illustrated review
por: Zhu, Annie, et al.
Publicado: (2022)

Circulating activated protein C levels are not increased in septic patients treated with recombinant human soluble thrombomodulin
por: Arishima, Takuro, et al.
Publicado: (2018)

Damage-associated molecular patterns and fibrinolysis perturbation are associated with lethal outcomes in traumatic injury
por: Shimono, Kenshin, et al.
Publicado: (2023)

Anthocyanins Extracted from Oryza sativa L. Prevent Fluorouracil-Induced Nuclear Factor-κB Activation in Oral Mucositis: In Vitro and In Vivo Studies
por: Tancharoen, Salunya, et al.
Publicado: (2018)

Recombinant Thrombomodulin Suppresses Histone-Induced Neutrophil Extracellular Trap Formation
por: Shrestha, Binita, et al.
Publicado: (2019)

Silver Jubilee of Stroke Thrombolysis With Alteplase: Evolution of the Therapeutic Window
por: Pan, Yuanmei, et al.
Publicado: (2021)

Effect of Apixaban Pretreatment on Alteplase-Induced Thrombolysis: An In Vitro Study
por: Thalerová, Sandra, et al.
Publicado: (2021)

Intravenous thrombolysis for acute ischemic stroke: From alteplase to tenecteplase
por: Yang, Nan, et al.
Publicado: (2023)

Circulating histone H3 levels are increased in septic mice in a neutrophil-dependent manner: preclinical evaluation of a novel sandwich ELISA for histone H3
por: Ito, Takashi, et al.
Publicado: (2018)

Downregulation of Tumor Promotor Genes in Oryza Sativa Linn.-Induced Antiproliferative Activity of Human Squamous Carcinoma Cells
por: Leenutaphong, Petchpailin, et al.
Publicado: (2023)

Risk Factors for Early Intracerebral Hemorrhage after Intravenous Thrombolysis with Alteplase
por: Lin, Xianda, et al.
Publicado: (2020)

Cleavage of Host Cytokeratin-6 by Lysine-Specific Gingipain Induces Gingival Inflammation in Periodontitis Patients
por: Tancharoen, Salunya, et al.
Publicado: (2015)

Omeprazole preserves the RER in chief cells and enhances re-epithelialization of parietal cells with SOD and AQP-4 up-regulation in ethanol-induced gastritis rats
por: Kengkoom, Kanchana, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_jl815ic7m1e72oqmci767dtgtd