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Genome-wide scan of the effect of common nsSNPs on colorectal cancer survival outcome

BACKGROUND: We conducted a genome-wide scan to identify non-synonymous SNPs (nsSNPs) that might influence survival after a diagnosis of colorectal cancer (CRC). METHODS: We genotyped 7679 nsSNPs in 1939 Scottish patients from the Scottish Colorectal Cancer Study recruited soon after a CRC diagnosis...

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Detalles Bibliográficos
Autores principales: Theodoratou, Evropi, Farrington, Susan M, Timofeeva, Maria, Din, Farhat VN, Svinti, Victoria, Tenesa, Albert, Liu, Tao, Lindblom, Annika, Gallinger, Steven, Campbell, Harry, Dunlop, Malcolm G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203849/
https://www.ncbi.nlm.nih.gov/pubmed/30135471
http://dx.doi.org/10.1038/s41416-018-0117-7