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Loss of amphiregulin reduces myoepithelial cell coverage of mammary ducts and alters breast tumor growth
BACKGROUND: Amphiregulin (AREG), a ligand of the epidermal growth factor receptor, is not only essential for proper mammary ductal development, but also associated with breast cancer proliferation and growth. In the absence of AREG, mammary ductal growth is stunted and fails to expand. Furthermore,...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203982/ https://www.ncbi.nlm.nih.gov/pubmed/30367629 http://dx.doi.org/10.1186/s13058-018-1057-0 |