Loss of amphiregulin reduces myoepithelial cell coverage of mammary ducts and alters breast tumor growth

BACKGROUND: Amphiregulin (AREG), a ligand of the epidermal growth factor receptor, is not only essential for proper mammary ductal development, but also associated with breast cancer proliferation and growth. In the absence of AREG, mammary ductal growth is stunted and fails to expand. Furthermore,...

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Detalles Bibliográficos
Autores principales: Mao, Serena P. H., Park, Minji, Cabrera, Ramon M., Christin, John R., Karagiannis, George S., Oktay, Maja H., Zaiss, Dietmar M. W., Abrams, Scott I., Guo, Wenjun, Condeelis, John S., Kenny, Paraic A., Segall, Jeffrey E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203982/
https://www.ncbi.nlm.nih.gov/pubmed/30367629
http://dx.doi.org/10.1186/s13058-018-1057-0

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