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Reduced gut microbiome protects from alcohol-induced neuroinflammation and alters intestinal and brain inflammasome expression

BACKGROUND: The end-organ effects of alcohol span throughout the entire body, from the gastrointestinal tract to the central nervous system (CNS). In the intestine, alcohol use changes the microbiome composition and increases gut permeability allowing translocation of microbial components into the c...

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Detalles Bibliográficos
Autores principales: Lowe, Patrick P., Gyongyosi, Benedek, Satishchandran, Abhishek, Iracheta-Vellve, Arvin, Cho, Yeonhee, Ambade, Aditya, Szabo, Gyongyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203993/
https://www.ncbi.nlm.nih.gov/pubmed/30368255
http://dx.doi.org/10.1186/s12974-018-1328-9