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Sorafenib and docosahexaenoic acid act in synergy to suppress cancer cell viability: a role of heme oxygenase 1

BACKGROUND: Docosahexaenoic acid (DHA) is a long chain n-3 polyunsaturated fatty acid that has anticancer activity. Heme oxygenase 1 (HO-1) is a potential therapeutic target due to its cytoprotective activity in cancer cells. We recently reported that DHA induces HO-1 gene transcription in human can...

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Detalles Bibliográficos
Autores principales: Jiao, Yang, Watts, Tanya, Xue, Jing, Hannafon, Bethany, Ding, Wei-Qun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204058/
https://www.ncbi.nlm.nih.gov/pubmed/30367621
http://dx.doi.org/10.1186/s12885-018-4946-9