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Chromatin run-on and sequencing maps the transcriptional regulatory landscape of glioblastoma multiforme

The human genome encodes a variety of poorly understood RNA species that remain challenging to identify using existing genomic tools. We developed chromatin run-on and sequencing (ChRO-seq) to map the location of RNA polymerase using virtually any input sample, including samples with degraded RNA th...

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Detalles Bibliográficos
Autores principales: Chu, Tinyi, Rice, Edward J., Booth, Gregory T., Salamanca, H. Hans, Wang, Zhong, Core, Leighton J., Longo, Sharon L, Corona, Robert J., Chin, Lawrence S., Lis, John T., Kwak, Hojoong, Danko, Charles G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204104/
https://www.ncbi.nlm.nih.gov/pubmed/30349114
http://dx.doi.org/10.1038/s41588-018-0244-3