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Chromatin run-on and sequencing maps the transcriptional regulatory landscape of glioblastoma multiforme
The human genome encodes a variety of poorly understood RNA species that remain challenging to identify using existing genomic tools. We developed chromatin run-on and sequencing (ChRO-seq) to map the location of RNA polymerase using virtually any input sample, including samples with degraded RNA th...
Autores principales: | Chu, Tinyi, Rice, Edward J., Booth, Gregory T., Salamanca, H. Hans, Wang, Zhong, Core, Leighton J., Longo, Sharon L, Corona, Robert J., Chin, Lawrence S., Lis, John T., Kwak, Hojoong, Danko, Charles G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204104/ https://www.ncbi.nlm.nih.gov/pubmed/30349114 http://dx.doi.org/10.1038/s41588-018-0244-3 |
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