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Structures of filaments from Pick’s disease reveal a novel tau protein fold
The ordered assembly of tau protein into abnormal filamentous inclusions underlies many human neurodegenerative diseases(1). Tau assemblies appear to spread through specific neural networks in each disease(2), with short filaments having the greatest seeding activity(3). The abundance of tau inclusi...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204212/ https://www.ncbi.nlm.nih.gov/pubmed/30158706 http://dx.doi.org/10.1038/s41586-018-0454-y |