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All-optical synaptic electrophysiology probes mechanism of ketamine-induced disinhibition

Optical assays of synaptic strength would greatly facilitate studies of neuronal transmission and its dysregulation in disease. Here we introduce a genetic toolbox for all-optical interrogation of synaptic electrophysiology (‘synOptopatch’) via mutually exclusive expression of a channelrhodopsin act...

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Detalles Bibliográficos
Autores principales: Fan, Linlin Z., Nehme, Ralda, Adam, Yoav, Jung, Eun Sun, Wu, Hao, Eggan, Kevin, Arnold, Don B., Cohen, Adam E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204345/
https://www.ncbi.nlm.nih.gov/pubmed/30275587
http://dx.doi.org/10.1038/s41592-018-0142-8