Infection Augments Expression of Mechanosensing Piezo1 Channels in Amyloid Plaque-Reactive Astrocytes

A defining pathophysiological hallmark of Alzheimer’s disease (AD) is the amyloid plaque; an extracellular deposit of aggregated fibrillar Aβ(1-42) peptides. Amyloid plaques are hard, brittle structures scattered throughout the hippocampus and cerebral cortex and are thought to cause hyperphosphoryl...

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Detalles Bibliográficos
Autores principales: Velasco-Estevez, María, Mampay, Myrthe, Boutin, Hervé, Chaney, Aisling, Warn, Peter, Sharp, Andrew, Burgess, Ellie, Moeendarbary, Emad, Dev, Kumlesh K., Sheridan, Graham K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Aging Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204357/
https://www.ncbi.nlm.nih.gov/pubmed/30405400
http://dx.doi.org/10.3389/fnagi.2018.00332

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204357/
https://www.ncbi.nlm.nih.gov/pubmed/30405400
http://dx.doi.org/10.3389/fnagi.2018.00332

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