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Infection Augments Expression of Mechanosensing Piezo1 Channels in Amyloid Plaque-Reactive Astrocytes

A defining pathophysiological hallmark of Alzheimer’s disease (AD) is the amyloid plaque; an extracellular deposit of aggregated fibrillar Aβ(1-42) peptides. Amyloid plaques are hard, brittle structures scattered throughout the hippocampus and cerebral cortex and are thought to cause hyperphosphoryl...

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Detalles Bibliográficos
Autores principales:	Velasco-Estevez, María, Mampay, Myrthe, Boutin, Hervé, Chaney, Aisling, Warn, Peter, Sharp, Andrew, Burgess, Ellie, Moeendarbary, Emad, Dev, Kumlesh K., Sheridan, Graham K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Aging Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204357/ https://www.ncbi.nlm.nih.gov/pubmed/30405400 http://dx.doi.org/10.3389/fnagi.2018.00332

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