Dietary Zinc Supplementation Prevents Autism Related Behaviors and Striatal Synaptic Dysfunction in Shank3 Exon 13–16 Mutant Mice

The SHANK family of synaptic proteins (SHANK1–3) are master regulators of the organizational structure of excitatory synapses in the brain. Mutations in SHANK1–3 are prevalent in patients with autism spectrum disorders (ASD), and loss of one copy of SHANK3 causes Phelan-McDermid Syndrome, a syndrome...

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Detalles Bibliográficos
Autores principales: Fourie, Chantelle, Vyas, Yukti, Lee, Kevin, Jung, Yewon, Garner, Craig C., Montgomery, Johanna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204368/
https://www.ncbi.nlm.nih.gov/pubmed/30405356
http://dx.doi.org/10.3389/fncel.2018.00374

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204368/
https://www.ncbi.nlm.nih.gov/pubmed/30405356
http://dx.doi.org/10.3389/fncel.2018.00374

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