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A Brief Overview of Two Major Strategies in Diversity-Oriented Synthesis: Build/Couple/Pair and Ring-Distortion

In the interdisciplinary research field of chemical biology and drug discovery, diversity-oriented synthesis (DOS) has become indispensable in the construction of novel small-molecule libraries rich in skeletal and stereochemical diversity. DOS aims to populate the unexplored chemical space with new...

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Detalles Bibliográficos
Autores principales: Yi, Sihyeong, Varun, Begur Vasanthkumar, Choi, Yoona, Park, Seung Bum
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204370/
https://www.ncbi.nlm.nih.gov/pubmed/30406085
http://dx.doi.org/10.3389/fchem.2018.00507