DNA Sliding Clamps as Therapeutic Targets

Chromosomal DNA replication is achieved by an assembly of multi-protein complexes at the replication fork. DNA sliding clamps play an important role in this assembly and are essential for cell viability. Inhibitors of bacterial (β-clamp) and eukaryal DNA clamps, proliferating cell nuclear antigen (P...

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Detalles Bibliográficos
Autores principales: Altieri, Amanda S., Kelman, Zvi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204406/
https://www.ncbi.nlm.nih.gov/pubmed/30406112
http://dx.doi.org/10.3389/fmolb.2018.00087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204406/
https://www.ncbi.nlm.nih.gov/pubmed/30406112
http://dx.doi.org/10.3389/fmolb.2018.00087

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