ENPP1-Fc prevents neointima formation in generalized arterial calcification of infancy through the generation of AMP

Generalized arterial calcification of infancy (GACI) is associated with widespread arterial calcification and stenoses and is caused by mutations in ENPP1. ENPP1 encodes for ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1), which cleaves ATP to generate inorganic pyrophosphate (PP(i)) and...

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Detalles Bibliográficos
Autores principales: Nitschke, Yvonne, Yan, Yan, Buers, Insa, Kintziger, Kristina, Askew, Kim, Rutsch, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204430/
https://www.ncbi.nlm.nih.gov/pubmed/30369595
http://dx.doi.org/10.1038/s12276-018-0163-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204430/
https://www.ncbi.nlm.nih.gov/pubmed/30369595
http://dx.doi.org/10.1038/s12276-018-0163-5

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