Cargando…

ENPP1-Fc prevents neointima formation in generalized arterial calcification of infancy through the generation of AMP

Generalized arterial calcification of infancy (GACI) is associated with widespread arterial calcification and stenoses and is caused by mutations in ENPP1. ENPP1 encodes for ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1), which cleaves ATP to generate inorganic pyrophosphate (PP(i)) and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nitschke, Yvonne, Yan, Yan, Buers, Insa, Kintziger, Kristina, Askew, Kim, Rutsch, Frank
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204430/ https://www.ncbi.nlm.nih.gov/pubmed/30369595 http://dx.doi.org/10.1038/s12276-018-0163-5

Ejemplares similares

ENPP1-Fc prevents mortality and vascular calcifications in rodent model of generalized arterial calcification of infancy
por: Albright, Ronald A., et al.
Publicado: (2015)

Generalized arterial calcification of infancy and pseudoxanthoma elasticum: two sides of the same coin
por: Nitschke, Yvonne, et al.
Publicado: (2012)

Molecular diagnosis of generalized arterial calcification of infancy (GACI)
por: Kalal, Iravathy Goud, et al.
Publicado: (2012)

Effects of etidronate on the Enpp1(−/−) mouse model of generalized arterial calcification of infancy
por: HUESA, CARMEN, et al.
Publicado: (2015)

Improved Reversion of Calcifications in Porcine Aortic Heart Valves Using Elastin-Targeted Nanoparticles
por: Feldmann, Anja, et al.
Publicado: (2023)

Mutant Enpp1(asj) mice as a model for generalized arterial calcification of infancy
por: Li, Qiaoli, et al.
Publicado: (2013)

Ectopic Calcification and Hypophosphatemic Rickets: Natural History of ENPP1 and ABCC6 Deficiencies
por: Ferreira, Carlos R, et al.
Publicado: (2021)

Generalized arterial calcification of infancy with a novel ENPP1 mutation: a case report
por: Brunod, Iole, et al.
Publicado: (2018)

Lmbrd1 expression is essential for the initiation of gastrulation
por: Buers, Insa, et al.
Publicado: (2016)

ENPP1 enzyme replacement therapy improves blood pressure and cardiovascular function in a mouse model of generalized arterial calcification of infancy
por: Khan, Tayeba, et al.
Publicado: (2018)

ENPP1 variants in patients with GACI and PXE expand the clinical and genetic heterogeneity of heritable disorders of ectopic calcification
por: Ralph, Douglas, et al.
Publicado: (2022)

CRLF1 and CLCF1 in Development, Health and Disease
por: Crisponi, Laura, et al.
Publicado: (2022)

Variable patterns of ectopic mineralization in Enpp1(asj-2J) mice, a model for generalized arterial calcification of infancy
por: Siu, Sarah Y., et al.
Publicado: (2016)

Zebrafish enpp1 mutants exhibit pathological mineralization, mimicking features of generalized arterial calcification of infancy (GACI) and pseudoxanthoma elasticum (PXE)
por: Apschner, Alexander, et al.
Publicado: (2014)

Case report: A rare homozygous variation in the ENPP1 gene, presenting with generalized arterial calcification of infancy in a Chinese infant
por: Lu, Pengtao, et al.
Publicado: (2023)

Spontaneous asj-2J Mutant Mouse as a Model for Generalized Arterial Calcification of Infancy: A Large Deletion/Insertion Mutation in the Enpp1 Gene
por: Li, Qiaoli, et al.
Publicado: (2014)

Elevated dietary magnesium during pregnancy and postnatal life prevents ectopic mineralization in Enpp1(asj) mice, a model for generalized arterial calcification of infancy
por: Kingman, Joshua, et al.
Publicado: (2017)

Prospective phenotyping of long-term survivors of Generalized Arterial Calcification of Infancy (GACI)
por: Ferreira, Carlos R., et al.
Publicado: (2020)

Improving the Pharmacodynamics and In Vivo Activity of ENPP1‐Fc Through Protein and Glycosylation Engineering
por: Stabach, Paul R., et al.
Publicado: (2020)

Expression of NPP1 is regulated during atheromatous plaque calcification
por: Nitschke, Yvonne, et al.
Publicado: (2011)

Association of ENPP1 gene polymorphisms with hand osteoarthritis in a Chuvasha population
por: Suk, Eun-Kyung, et al.
Publicado: (2005)

Influence of valsartan-eluting stent on neointima formation
por: Guihua, Li, et al.
Publicado: (2010)

Uremia does not affect neointima formation in mice
por: Aarup, Annemarie, et al.
Publicado: (2017)

Characterization of hearing-impairment in Generalized Arterial Calcification of Infancy (GACI)
por: Theng, Elizabeth H., et al.
Publicado: (2022)

Estimation of ENPP1 deficiency genetic prevalence using a comprehensive literature review and population databases
por: Chunn, Lauren M., et al.
Publicado: (2022)

Deficiency of neuropeptide Y attenuates neointima formation after vascular injury in mice
por: Peng, Song, et al.
Publicado: (2023)

A proteomics analysis of neointima formation on decellularized vascular grafts reveals regenerative alterations in protein signature running head: Proteomics analysis of neointima formation
por: Chen, Chunyang, et al.
Publicado: (2022)

Generalized Arterial Calcification of Infancy (GACI): Optimizing Care with a Multidisciplinary Approach
por: Kawai, Kenji, et al.
Publicado: (2022)

Suppression of neointima formation by targeting β-catenin/TCF pathway
por: Williams, Helen, et al.
Publicado: (2016)

Oral Charcoal Adsorbents Attenuate Neointima Formation of Arteriovenous Fistulas
por: Shih, Yu-Chung, et al.
Publicado: (2020)

Differential Role for Activating FcγRIII in Neointima Formation After Arterial Injury and Diet-Induced Chronic Atherosclerosis in Apolipoprotein E-Deficient Mice
por: Asare, Yaw, et al.
Publicado: (2020)

The novel mineralocorticoid receptor antagonist finerenone attenuates neointima formation after vascular injury
por: Dutzmann, Jochen, et al.
Publicado: (2017)

Interferon regulatory factor 9 is critical for neointima formation following vascular injury
por: Zhang, Shu-Min, et al.
Publicado: (2014)

A New Enpp1 allele, Enpp1(ttw-Ham), Identified in an ICR Closed Colony
por: Takabayashi, Shuji, et al.
Publicado: (2014)

Lysophosphatidic Acid Induces Neointima Formation Through PPARγ Activation
por: Zhang, Chunxiang, et al.
Publicado: (2004)

Rosuvastatin reduces neointima formation in a rat model of balloon injury
por: Preusch, MR, et al.
Publicado: (2010)

Antiphospholipid Antibodies Attenuate Endothelial Repair and Promote Neointima Formation in Mice
por: Ulrich, Victoria, et al.
Publicado: (2014)

Role of ENPP1 on Adipocyte Maturation
por: Liang, Jian, et al.
Publicado: (2007)

ENPP2 Methylation in Health and Cancer
por: Panagopoulou, Maria, et al.
Publicado: (2021)

ENPP1, an Old Enzyme with New Functions, and Small Molecule Inhibitors—A STING in the Tale of ENPP1
por: Onyedibe, Kenneth I., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_dt4n80artt3lf437gh9knpr7o8