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Protein acetylation in skeletal muscle mitochondria is involved in impaired fatty acid oxidation and exercise intolerance in heart failure

BACKGROUND: Exercise intolerance is a common clinical feature and is linked to poor prognosis in patients with heart failure (HF). Skeletal muscle dysfunction, including impaired energy metabolism in the skeletal muscle, is suspected to play a central role in this intolerance, but the underlying mec...

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Detalles Bibliográficos
Autores principales: Tsuda, Masaya, Fukushima, Arata, Matsumoto, Junichi, Takada, Shingo, Kakutani, Naoya, Nambu, Hideo, Yamanashi, Katsuma, Furihata, Takaaki, Yokota, Takashi, Okita, Koichi, Kinugawa, Shintaro, Anzai, Toshihisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204592/
https://www.ncbi.nlm.nih.gov/pubmed/30168279
http://dx.doi.org/10.1002/jcsm.12322