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Imputation-Based Whole-Genome Sequence Association Study Reveals Constant and Novel Loci for Hematological Traits in a Large-Scale Swine F(2) Resource Population

The whole-genome sequences of progenies with low-density single-nucleotide polymorphism (SNP) genotypes can be imputed with high accuracy based on the deep-coverage sequences of key ancestors. With this imputation technology, a more powerful genome-wide association study (GWAS) can be carried out us...

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Detalles Bibliográficos
Autores principales: Yan, Guorong, Guo, Tianfu, Xiao, Shijun, Zhang, Feng, Xin, Wenshui, Huang, Tao, Xu, Wenwu, Li, Yiping, Zhang, Zhiyan, Huang, Lusheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204663/
https://www.ncbi.nlm.nih.gov/pubmed/30405681
http://dx.doi.org/10.3389/fgene.2018.00401