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Effect of Hypoxia on the Pathogenesis of Acinetobacter baumannii and Pseudomonas aeruginosa In Vitro and in Murine Experimental Models of Infection

Hypoxia modulates bacterial virulence and the inflammation response through hypoxia-inducible factor 1α (HIF-1α). Here we study the influence of hypoxia on Acinetobacter baumannii and Pseudomonas aeruginosa infections. In vitro, hypoxia increases the bactericidal activities of epithelial cells again...

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Detalles Bibliográficos
Autores principales: Gil-Marqués, María Luisa, Pachón-Ibáñez, María Eugenía, Pachón, Jerónimo, Smani, Younes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204731/
https://www.ncbi.nlm.nih.gov/pubmed/30082478
http://dx.doi.org/10.1128/IAI.00543-18