Genome Plasticity of agr-Defective Staphylococcus aureus during Clinical Infection

Therapy for bacteremia caused by Staphylococcus aureus is often ineffective, even when treatment conditions are optimal according to experimental protocols. Adapted subclones, such as those bearing mutations that attenuate agr-mediated virulence activation, are associated with persistent infection a...

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Detalles Bibliográficos
Autores principales: Altman, Deena R., Sullivan, Mitchell J., Chacko, Kieran I., Balasubramanian, Divya, Pak, Theodore R., Sause, William E., Kumar, Krishan, Sebra, Robert, Deikus, Gintaras, Attie, Oliver, Rose, Hannah, Lewis, Martha, Fulmer, Yi, Bashir, Ali, Kasarskis, Andrew, Schadt, Eric E., Richardson, Anthony R., Torres, Victor J., Shopsin, Bo, van Bakel, Harm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Molecular Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204747/
https://www.ncbi.nlm.nih.gov/pubmed/30061376
http://dx.doi.org/10.1128/IAI.00331-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204747/
https://www.ncbi.nlm.nih.gov/pubmed/30061376
http://dx.doi.org/10.1128/IAI.00331-18

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