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Novel solid-phase strategy for the synthesis of ligand-targeted fluorescent-labelled chelating peptide conjugates as a theranostic tool for cancer

In this article, we have successfully designed and demonstrated a novel continuous process for assembling targeting ligands, peptidic spacers, fluorescent tags and a chelating core for the attachment of cytotoxic molecules, radiotracers, nanomaterials in a standard Fmoc solid-phase peptide synthesis...

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Detalles Bibliográficos
Autores principales: Sengupta, Sagnik, Krishnan, Mena Asha, Dudhe, Premansh, Reddy, Ramesh B, Giri, Bishnubasu, Chattopadhyay, Sudeshna, Chelvam, Venkatesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204756/
https://www.ncbi.nlm.nih.gov/pubmed/30410628
http://dx.doi.org/10.3762/bjoc.14.244