Gold-catalyzed post-Ugi alkyne hydroarylation for the synthesis of 2-quinolones

A series of propargylamides containing an electron-rich benzene ring was prepared through the Ugi reaction of 3,5-dimethoxyaniline with various propiolic acids, aldehydes and isocyanides. Subjecting these adducts to a gold-catalyzed intramolecular alkyne hydroarylation process allowed to efficiently...

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Detalles Bibliográficos
Autores principales: Du, Xiaochen, Huang, Jianjun, Nechaev, Anton A, Yao, Ruwei, Gong, Jing, Van der Eycken, Erik V, Pereshivko, Olga P, Peshkov, Vsevolod A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2018
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204774/
https://www.ncbi.nlm.nih.gov/pubmed/30410618
http://dx.doi.org/10.3762/bjoc.14.234

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204774/
https://www.ncbi.nlm.nih.gov/pubmed/30410618
http://dx.doi.org/10.3762/bjoc.14.234

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