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Platform development for expression and purification of stable isotope labeled monoclonal antibodies in Escherichia coli

The widespread use of monoclonal antibodies (mAbs) as a platform for therapeutic drug development in the pharmaceutical industry has led to an increased interest in robust experimental approaches for assessment of mAb structure, stability and dynamics. The ability to enrich proteins with stable isot...

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Detalles Bibliográficos
Autores principales: Reddy, Prasad T., Brinson, Robert G., Hoopes, J. Todd, McClung, Colleen, Ke, Na, Kashi, Lila, Berkmen, Mehmet, Kelman, Zvi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204800/
https://www.ncbi.nlm.nih.gov/pubmed/30060704
http://dx.doi.org/10.1080/19420862.2018.1496879