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Platform development for expression and purification of stable isotope labeled monoclonal antibodies in Escherichia coli
The widespread use of monoclonal antibodies (mAbs) as a platform for therapeutic drug development in the pharmaceutical industry has led to an increased interest in robust experimental approaches for assessment of mAb structure, stability and dynamics. The ability to enrich proteins with stable isot...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204800/ https://www.ncbi.nlm.nih.gov/pubmed/30060704 http://dx.doi.org/10.1080/19420862.2018.1496879 |