Synthesis and biological evaluation of 1,2-disubsubstituted 4-quinolone analogues of Pseudonocardia sp. natural products

A series of analogues of Pseudonocardia sp. natural products were synthesized, which have been reported to possess potent antibacterial activity against Helicobacter pylori and induce growth defects in Escherichia coli and Staphylococcus aureus. Taking inspiration from a methodology used in our tota...

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Detalles Bibliográficos
Autores principales: Geddis, Stephen M, Coroama, Teodora, Forrest, Suzanne, Hodgkinson, James T, Welch, Martin, Spring, David R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2018
Materias:
Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204808/
https://www.ncbi.nlm.nih.gov/pubmed/30410629
http://dx.doi.org/10.3762/bjoc.14.245

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204808/
https://www.ncbi.nlm.nih.gov/pubmed/30410629
http://dx.doi.org/10.3762/bjoc.14.245

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