The design and synthesis of an antibacterial phenothiazine–siderophore conjugate

Siderophore–antibiotic conjugates consist of an antibiotic covalently linked by a tether to a siderophore. Such conjugates can demonstrate enhanced uptake and internalisation to the bacterial cell resulting in significantly reduced MIC values and extended spectrum of activity. Phenothiazines are a c...

Descripción completa

Detalles Bibliográficos
Autores principales: Tarapdar, Abed, Norris, James K S, Sampson, Oliver, Mukamolova, Galina, Hodgkinson, James T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2018
Materias:
Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204836/
https://www.ncbi.nlm.nih.gov/pubmed/30410626
http://dx.doi.org/10.3762/bjoc.14.242

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204836/
https://www.ncbi.nlm.nih.gov/pubmed/30410626
http://dx.doi.org/10.3762/bjoc.14.242

Ejemplares similares