pH-sensitive PEGylation of RIPL peptide-conjugated nanostructured lipid carriers: design and in vitro evaluation

BACKGROUND: RIPL peptide (IPLVVPLRRRRRRRRC)-conjugated nanostructured lipid carriers (RIPL-NLCs) can facilitate selective drug delivery to hepsin (Hpn)-expressing cancer cells, but they exhibit low stability in the blood. Generally, biocompatible and nontoxic poly(ethylene glycol) surface modificati...

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Detalles Bibliográficos
Autores principales: Kim, Chang Hyun, Sa, Cheol-Ki, Goh, Min Su, Lee, Eun Seok, Kang, Tae Hoon, Yoon, Ho Yub, Battogtokh, Gantumur, Ko, Young Tag, Choi, Young Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204877/
https://www.ncbi.nlm.nih.gov/pubmed/30425481
http://dx.doi.org/10.2147/IJN.S184355

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204877/
https://www.ncbi.nlm.nih.gov/pubmed/30425481
http://dx.doi.org/10.2147/IJN.S184355

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