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Nuclear orphan receptor NR2F6 as a safeguard against experimental murine colitis

OBJECTIVE: Nuclear receptors are known to regulate both immune and barrier functions in the GI tract. The nuclear orphan receptor NR2F6 has been shown to suppress the expression of proinflammatory cytokines in T lymphocytes. NR2F6 gene expression is reduced in patients with IBS or UC, but its functi...

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Detalles Bibliográficos
Autores principales: Klepsch, Victoria, Gerner, Romana R, Klepsch, Sebastian, Olson, William J, Tilg, Herbert, Moschen, Alexander R, Baier, Gottfried, Hermann-Kleiter, Natascha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204953/
https://www.ncbi.nlm.nih.gov/pubmed/28779026
http://dx.doi.org/10.1136/gutjnl-2016-313466