Cargando…
Nuclear orphan receptor NR2F6 as a safeguard against experimental murine colitis
OBJECTIVE: Nuclear receptors are known to regulate both immune and barrier functions in the GI tract. The nuclear orphan receptor NR2F6 has been shown to suppress the expression of proinflammatory cytokines in T lymphocytes. NR2F6 gene expression is reduced in patients with IBS or UC, but its functi...
Autores principales: | Klepsch, Victoria, Gerner, Romana R, Klepsch, Sebastian, Olson, William J, Tilg, Herbert, Moschen, Alexander R, Baier, Gottfried, Hermann-Kleiter, Natascha |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204953/ https://www.ncbi.nlm.nih.gov/pubmed/28779026 http://dx.doi.org/10.1136/gutjnl-2016-313466 |
Ejemplares similares
-
Nuclear Receptors Regulate Intestinal Inflammation in the Context of IBD
por: Klepsch, Victoria, et al.
Publicado: (2019) -
Targeting the orphan nuclear receptor NR2F6 in T cells primes tumors for immune checkpoint therapy
por: Klepsch, Victoria, et al.
Publicado: (2020) -
Orphan Nuclear Receptor NR2F6 Suppresses T Follicular Helper Cell Accumulation through Regulation of IL-21
por: Olson, William J., et al.
Publicado: (2019) -
The Nuclear Orphan Receptor NR2F6 Is a Central Checkpoint for Cancer Immune Surveillance
por: Hermann-Kleiter, Natascha, et al.
Publicado: (2015) -
Loss of the orphan nuclear receptor NR2F6 enhances CD8(+) T-cell memory via IFN-γ
por: Jakic, Bojana, et al.
Publicado: (2021)