Immune-mediated effects targeting hepatitis C virus in a syngeneic replicon cell transplantation mouse model

OBJECTIVE: HCV is characterised by its ability to establish chronic infection in hepatocytes and to replicate in the presence of an inflammation. We mimicked this situation in vivo in immune-competent mice by syngeneic transplantation of HCV replicon-containing mouse hepatoma cells. DESIGN: A total...

Descripción completa

Detalles Bibliográficos
Autores principales: Levander, Sepideh, Holmström, Fredrik, Frelin, Lars, Ahlén, Gustaf, Rupp, Daniel, Long, Gang, Bartenschlager, Ralf, Sällberg, Matti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Hepatology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204962/
https://www.ncbi.nlm.nih.gov/pubmed/28646094
http://dx.doi.org/10.1136/gutjnl-2016-313579

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204962/
https://www.ncbi.nlm.nih.gov/pubmed/28646094
http://dx.doi.org/10.1136/gutjnl-2016-313579

Ejemplares similares