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Immune-mediated effects targeting hepatitis C virus in a syngeneic replicon cell transplantation mouse model

OBJECTIVE: HCV is characterised by its ability to establish chronic infection in hepatocytes and to replicate in the presence of an inflammation. We mimicked this situation in vivo in immune-competent mice by syngeneic transplantation of HCV replicon-containing mouse hepatoma cells. DESIGN: A total...

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Detalles Bibliográficos
Autores principales:	Levander, Sepideh, Holmström, Fredrik, Frelin, Lars, Ahlén, Gustaf, Rupp, Daniel, Long, Gang, Bartenschlager, Ralf, Sällberg, Matti
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2018
Materias:	Hepatology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6204962/ https://www.ncbi.nlm.nih.gov/pubmed/28646094 http://dx.doi.org/10.1136/gutjnl-2016-313579

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