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Human mast cells promote colon cancer growth via bidirectional crosstalk: studies in 2D and 3D coculture models

Chronic inflammation drives the development of colorectal cancer (CRC), where tumor-infiltrating immune cells interact with cancer cells in a dynamic crosstalk. Mast cells (MC), one of earliest recruited immune cells, accumulate in CRC tissues and their density is correlated with cancer progression....

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Detalles Bibliográficos
Autores principales: Yu, Yingxin, Blokhuis, Bart, Derks, Yvonne, Kumari, Sangeeta, Garssen, Johan, Redegeld, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205014/
https://www.ncbi.nlm.nih.gov/pubmed/30377568
http://dx.doi.org/10.1080/2162402X.2018.1504729