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Human mast cells promote colon cancer growth via bidirectional crosstalk: studies in 2D and 3D coculture models
Chronic inflammation drives the development of colorectal cancer (CRC), where tumor-infiltrating immune cells interact with cancer cells in a dynamic crosstalk. Mast cells (MC), one of earliest recruited immune cells, accumulate in CRC tissues and their density is correlated with cancer progression....
Autores principales: | Yu, Yingxin, Blokhuis, Bart, Derks, Yvonne, Kumari, Sangeeta, Garssen, Johan, Redegeld, Frank |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205014/ https://www.ncbi.nlm.nih.gov/pubmed/30377568 http://dx.doi.org/10.1080/2162402X.2018.1504729 |
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