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T cell receptor richness in peripheral blood increases after cetuximab therapy and correlates with therapeutic response

The role of T cell receptor (TCR) signaling for adaptive immune responses is essential. The ability to respond to a broad spectrum of tumor antigens requires an adaptive selection of various TCR. So far, little is known about the role of TCR richness and clonality in the cellular immune response to...

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Detalles Bibliográficos
Autores principales: Kansy, Benjamin A., Shayan, Gulidanna, Jie, Hyun-Bae, Gibson, Sandra P., Lei, Yu L., Brandau, Sven, Lang, Stephan, Schmitt, Nicole C, Ding, Fei, Lin, Yan, Ferris, Robert L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205044/
https://www.ncbi.nlm.nih.gov/pubmed/30377562
http://dx.doi.org/10.1080/2162402X.2018.1494112