Oral methylnaltrexone is efficacious and well tolerated for the treatment of opioid-induced constipation in patients with chronic noncancer pain receiving concomitant methadone

PURPOSE: To evaluate the safety and efficacy of oral methylnaltrexone for opioid-induced constipation (OIC). PATIENTS AND METHODS: This was a post hoc analysis of patients receiving methadone in a randomized, double-blind, placebo-controlled, Phase 3 trial. The trial included adults with chronic non...

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Detalles Bibliográficos
Autores principales: Webster, Lynn R, Israel, Robert J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205130/
https://www.ncbi.nlm.nih.gov/pubmed/30425563
http://dx.doi.org/10.2147/JPR.S160625

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205130/
https://www.ncbi.nlm.nih.gov/pubmed/30425563
http://dx.doi.org/10.2147/JPR.S160625

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