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Oral methylnaltrexone is efficacious and well tolerated for the treatment of opioid-induced constipation in patients with chronic noncancer pain receiving concomitant methadone

PURPOSE: To evaluate the safety and efficacy of oral methylnaltrexone for opioid-induced constipation (OIC). PATIENTS AND METHODS: This was a post hoc analysis of patients receiving methadone in a randomized, double-blind, placebo-controlled, Phase 3 trial. The trial included adults with chronic non...

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Detalles Bibliográficos
Autores principales:	Webster, Lynn R, Israel, Robert J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205130/ https://www.ncbi.nlm.nih.gov/pubmed/30425563 http://dx.doi.org/10.2147/JPR.S160625

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