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ATR suppresses the pro-tumorigenic functions of breast stromal fibroblasts

The ATR protein kinase is a master regulator of the cellular responses to DNA damage and replication stresses. Despite these crucial physiological roles, the implication of ATR in human carcinogenesis remains elusive. We have shown here that the ATR level is reduced in most cancer-associated fibrobl...

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Detalles Bibliográficos
Autores principales: Al-Ansari, Mysoon M., Aboussekhra, Abdelilah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205174/
https://www.ncbi.nlm.nih.gov/pubmed/30410668
http://dx.doi.org/10.18632/oncotarget.26159