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ATR suppresses the pro-tumorigenic functions of breast stromal fibroblasts
The ATR protein kinase is a master regulator of the cellular responses to DNA damage and replication stresses. Despite these crucial physiological roles, the implication of ATR in human carcinogenesis remains elusive. We have shown here that the ATR level is reduced in most cancer-associated fibrobl...
Autores principales: | Al-Ansari, Mysoon M., Aboussekhra, Abdelilah |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205174/ https://www.ncbi.nlm.nih.gov/pubmed/30410668 http://dx.doi.org/10.18632/oncotarget.26159 |
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