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Estradiol promotes rapid degradation of HER3 in ER-positive breast cancer cell line MCF-7

HER3, a member of the receptor tyrosine kinase super family, is overexpressed in a number of cancers, and is associated with malignant phenotypes. Control of the protein stability of the membrane, as well as nuclear receptors, has been known to be an important process affecting tumor cells; however,...

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Detalles Bibliográficos
Autores principales: Suga, Junko, Izumiyama, Keiko, Tanaka, Nobuyuki, Saji, Shigehira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205365/
https://www.ncbi.nlm.nih.gov/pubmed/30417127
http://dx.doi.org/10.1016/j.bbrep.2018.10.008