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Entropic contribution to enhanced thermal stability in the thermostable P450 CYP119
The enhanced thermostability of thermophilic proteins with respect to their mesophilic counterparts is often attributed to the enthalpy effect, arising from strong interactions between protein residues. Intuitively, these strong interresidue interactions will rigidify the biomolecules. However, the...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205451/ https://www.ncbi.nlm.nih.gov/pubmed/30297413 http://dx.doi.org/10.1073/pnas.1807473115 |