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Nonproteinogenic deep mutational scanning of linear and cyclic peptides

High-resolution structure–activity analysis of polypeptides requires amino acid structures that are not present in the universal genetic code. Examination of peptide and protein interactions with this resolution has been limited by the need to individually synthesize and test peptides containing non...

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Detalles Bibliográficos
Autores principales: Rogers, Joseph M., Passioura, Toby, Suga, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205457/
https://www.ncbi.nlm.nih.gov/pubmed/30301798
http://dx.doi.org/10.1073/pnas.1809901115