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Highly efficient siRNA transfection in macrophages using apoptotic body-mimic Ca-PS lipopolyplex

BACKGROUND: The discovery and development of RNA interference has made a tremendous contribution to the biochemical and biomedical field. However, liposomal transfection protocols to deliver siRNAs to certain types of cells, eg, immune cells, are not viable due to exceedingly low transfection effici...

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Detalles Bibliográficos
Autores principales: Lai, Yueyang, Xu, Xuebo, Zhu, Zhenyu, Hua, Zichun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205523/
https://www.ncbi.nlm.nih.gov/pubmed/30425477
http://dx.doi.org/10.2147/IJN.S176991