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Brain metastases in ALK-positive NSCLC – time to adjust current treatment algorithms

The progress in molecular biology has revolutionized systemic treatment of advanced non-small-cell lung cancer (NSCLC) from conventional chemotherapy to a treatment stratified by histology and genetic aberrations. Tumors harboring a translocation of the anaplastic-lymphoma-kinase (ALK) gene constitu...

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Detalles Bibliográficos
Autores principales: Griesinger, Frank, Roeper, Julia, Pöttgen, Christoph, Willborn, Kay C., Eberhardt, Wilfried E.E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205553/
https://www.ncbi.nlm.nih.gov/pubmed/30416687
http://dx.doi.org/10.18632/oncotarget.26073