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Brain metastases in ALK-positive NSCLC – time to adjust current treatment algorithms
The progress in molecular biology has revolutionized systemic treatment of advanced non-small-cell lung cancer (NSCLC) from conventional chemotherapy to a treatment stratified by histology and genetic aberrations. Tumors harboring a translocation of the anaplastic-lymphoma-kinase (ALK) gene constitu...
Autores principales: | Griesinger, Frank, Roeper, Julia, Pöttgen, Christoph, Willborn, Kay C., Eberhardt, Wilfried E.E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205553/ https://www.ncbi.nlm.nih.gov/pubmed/30416687 http://dx.doi.org/10.18632/oncotarget.26073 |
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