Electrochemical, spectroscopic and theoretical monitoring of anthracyclines’ interactions with DNA and ascorbic acid by adopting two routes: Cancer cell line studies

Pharmacodynamic interactions of three anthracycline antibiotics namely doxorubicin (DXH), epirubicin (EpiDXH) and daunorubicin (DNR) with DNA in the absence and presence of ascorbic acid (AA) as natural additive were monitored under physiological conditions (pH = 7.4, 4.7 and T = 309.5K). Route–1 (A...

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Detalles Bibliográficos
Autores principales: Perveen, Fouzia, Arshad, Nasima, Qureshi, Rumana, Nowsherwan, Jahanzaib, Sultan, Aiesha, Nosheen, Bushra, Rafique, Hummera
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205586/
https://www.ncbi.nlm.nih.gov/pubmed/30372448
http://dx.doi.org/10.1371/journal.pone.0205764

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205586/
https://www.ncbi.nlm.nih.gov/pubmed/30372448
http://dx.doi.org/10.1371/journal.pone.0205764

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