The autophagy inhibitor spautin-1, either alone or combined with doxorubicin, decreases cell survival and colony formation in canine appendicular osteosarcoma cells

Dogs diagnosed with appendicular osteosarcoma typically succumb to metastatic disease within a year of diagnosis. The current standard of care for curative intent, amputation followed by adjuvant chemotherapy, increases survival time but chemoresistance is a major contributor to mortality. Unfortuna...

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Detalles Bibliográficos
Autores principales: Schott, Courtney R., Ludwig, Latasha, Mutsaers, Anthony J., Foster, Robert A., Wood, Geoffrey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205606/
https://www.ncbi.nlm.nih.gov/pubmed/30372478
http://dx.doi.org/10.1371/journal.pone.0206427

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205606/
https://www.ncbi.nlm.nih.gov/pubmed/30372478
http://dx.doi.org/10.1371/journal.pone.0206427

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