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Microevolution in response to transient heme-iron restriction enhances intracellular bacterial community development and persistence

Bacterial pathogens must sense, respond and adapt to a myriad of dynamic microenvironmental stressors to survive. Adaptation is key for colonization and long-term ability to endure fluctuations in nutrient availability and inflammatory processes. We hypothesize that strains adapted to survive nutrie...

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Detalles Bibliográficos
Autores principales: Hardison, Rachael L., Harrison, Alistair, Wallace, Rachel M., Heimlich, Derek R., O’Bryan, Meghan E., Sebra, Robert P., Pinkett, Heather W., Justice, Sheryl S., Mason, Kevin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205647/
https://www.ncbi.nlm.nih.gov/pubmed/30332468
http://dx.doi.org/10.1371/journal.ppat.1007355